The clone
rangerBY JACOB GOLDSTEINjgoldstein@herald.com
A year and a half ago, Bernard Siegel was a Coral Gables personal
injury lawyer. Two weeks ago, he masterminded a worldwide conference
on cloning and stem cell research at the United Nations.
How did Siegel go from Coral Gables to the U.N. in 18 months?
The Raelians did it.
You remember the Raelians -- the group that believes aliens used
DNA to create life on Earth. A few years back, a company launched by
the Raelians' founder -- Clonaid -- announced at a Hollywood press
conference the birth of the world's first cloned baby. After the
story made headlines around the world, Siegel filed a lawsuit asking
the Broward Circuit Court to look into the baby's welfare.
''I used to do a lot of child advocacy work,'' said Siegel, who
is married and has two grown children. ``This alleged child was
nothing more than a typical milk-carton child being manipulated or
exploited.''
SCIENTIFIC CONCERN
The baby never turned up, and many experts concluded the story
was a hoax. But during the legal proceedings Siegel heard from
several scientists. Their concern: No one was educating the public
about the difference between reproductive cloning, which would
create cloned people, and therapeutic cloning, which is tied to
stem-cell research and could lead to breakthroughs in diabetes,
Parkinson's and paralysis, among other conditions.
So Siegel left his 30-year law career last year to found a
Miami-based nonprofit, the Genetics Policy Institute. His mission:
Convince key policymakers that reproductive cloning should be
banned, but therapeutic cloning and stem cell research should be
actively supported.
`CLARITY OF PURPOSE'
''There was a vacuum and I just happened to have the clarity of
purpose and the drive to do something,'' Siegel said.
And the constitution to withstand a political firestorm. With
President Bush's policy limiting stem cell research under attack by
some members of Congress, Nancy Reagan's recent public support of
stem-cell work and a pending $3 billion initiative to fund stem-cell
research in California, Siegel has found himself at the center of
one of the hottest subjects in medical research.
''He's emerging as one of the national leaders on this issue,
recognized by top scientists who traveled across the oceans to come
to his meeting in New York,'' said Daniel Perry, president of the
Coalition for the Advancement of Medical Research, which lobbies for
stem cell research.
The U.N. meeting focused on the difference between reproductive
and therapeutic cloning.
Scientists have demonstrated it's possible to take the DNA, or
genetic code, from an adult and insert it into an unfertilized egg.
Theoretically, this cell could be implanted into a woman's uterus
and grow into a cloned individual. This would be reproductive
cloning.
In therapeutic cloning, the egg is injected with DNA from an
adult, but it is never implanted in a woman's uterus. Instead, the
egg grows in a lab into a cell cluster that includes embryonic stem
cells, which can transform themselves into virtually any type of
cell or tissue. Scientists say these new cells could lead to
treatments for many major diseases.
In recent years, many of the world's leading scientific
associations have come out opposing reproductive cloning but
supporting therapeutic cloning.
RELIGIOUS GROUPS
But some religious groups, including the Catholic Church, oppose
all forms of cloning. The church believes that a human embryo is
created the moment the adult DNA is injected into the egg cell,
according to Rev. Alfred Cioffi, a Miami-based priest with a Ph.d in
bioethics.
''When we obtain human embryonic stem cells, we are destroying
embryos,'' Cioffi said.
Because of concerns like these, a U.N. proposal to ban all forms
of cloning came within one vote of passing a key committee last
fall. That prompted Siegel to take his message to the New York
institution.
He worked with legal advisors from several Asian delegations to
bring scientists from around the world to speak there earlier this
month. Delegates from about 60 nations turned out to hear the
scientists, according to Marc Pecsteen, who attended as a Belgian
delegate.
Siegel ''practically is the person who alone put together this
effort . . . one person at a time, one scientist at a time, one
organization at a time,'' said Camillo Ricordi, a University of
Miami diabetes researcher who serves on Siegel's advisory board and
who spoke at the conference. ``He's an incredibly driven
advocate.''
PENDING AT U.N.
The U.N. is slated to take up the cloning ban again this fall.
Pecsteen, whose delegation supports banning reproductive cloning but
believes countries should decide whether to ban therapeutic cloning,
said it is impossible to say whether the conference changed the
views of any delegates. But he welcomed the input from the
scientists.
''Last year there were many pro-life groups advocating a total
ban who were very active in the corridors of the meeting rooms
distributing papers, and there was nothing from the side of the
scientists,'' Pecsteen said. ``This is the first time the scientific
community has come forward with their views. In a way it creates a
new balance.''
Siegel, who called the U.N. conference ''the greatest achievement
of my professional life,'' remains the sole employee of the Genetics
Policy Institute. But he has grand ambitions.
''I'm building a global constituency,'' he said. ``We are going
to be a voice well into the 21st century.''
Jacob Goldstein is The Herald's new medical writer. |